Medical Cannabis
Cannabis use for medicinal purposes dates back at least 3,000 years. It was introduced into Western medicine in the 1840s by W.B. O’Shaughnessy, a surgeon who learned of its medicinal properties while working in India for the British East Indies Company. Its use was promoted for reported analgesic, sedative, anti-inflammatory, antispasmodic, and anti-convulsant effects. — National Cancer Institute | 2014
The Endocannabinoid System (ECS) is a homeostatic regulatory system that forms the cornerstone of a vast signaling network found in all vertebrates including humans. The ECS effectively ‘regulates regulation’ for physiological processes.
While it had been the conventional wisdom until recently that only cannabis harbored active agents affecting the endocannabinoid system, in recent decades the search has widened and identified numerous additional plants whose components stimulate, antagonize, or modulate different aspects of this system. These include common foodstuffs, herbs, spices, and more exotic ingredients: kava, chocolate, black pepper, and many others. — Ethan Russo | Beyond Cannabis: Plants and the Endocannabinoid System
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